Immunology NK Cells Receptors

Question: Portray the elements of NK cells receptors? Answer: NK cells or characteristic executioner cells are cytototoxic lymphocytes, noteworthy to the vertebrate intrinsic resistant framework. They act comparative like cytotoxic T cells. NK cells give quick reactions to tainted cells and furthermore respond during tumor arrangement. Invulnerable cells have the ability to distinguish significant histocompatibility complex or MHC, introduced on the contaminated cell surfaces, trigger cytokine discharge and this prompts cell apoptosis or cell lysis. NK cells have ability to distinguish focused on cells without the nearness of significant histocompatibility complex and antibodies and furthermore they take into consideration much quick invulnerable response inside the human framework. In this way, these cells are named as regular executioners, as they don't require cell actuation to decimate cells. This capacity is commonly fundamental as destructive cells, those don't have MHC 1 markers can't be recognized and decimated by various other safe cel ls, for instance: T lymphocyte cells. NK cell receptors Capacities Ly49 Actuating receptors, human have pseudogenic Ly49 for polymorphic MHC I atoms. NCR/Natural Cytotoxic Receptors Actuating receptors; upon incitement discharge gamma interferon and intervene NK murdering. CD94 Actuating receptors; recognize nonclassical or nonpolymorphic MHC I particles, for instance: HLA-E. Articulation of significant histocompatibility complex. Class I, E on the cell surfaces is dependent on the presence of nonamer peptide epitope (Lieto, 2005). These are gotten from signal grouping related with traditional MHC I atoms. This succession is created by sequential activity of sign peptidase and proteasome. This system is considered as circuitous and is supposed to be a decent method to examine the amount of polymorphic HLA atoms. CD16 Actuating receptors; these receptors can tie with immunoglobulin G and add to the capacity of counter acting agent subordinate cell-intervened cytotoxicity. These receptors are low partiality Fc receptors and connect to Fc area of antibodies immunoglobulin G. This unpredictable at that point actuates common executioner cells for of counter acting agent subordinate cell-intervened cytotoxicity (Kramer, Winger and Reuben, 2009). In the event that CD16 is absent in a specific neutrophil populace, it could be expected as the sign of rashness, which could have occurred as a result of left-move brought about by neutrophilic leukocytosis animated by bacterial disease or tissue corruption. KIRs or executioner cell immunoglobulin-like receptors Inhibitory receptors; these are the principle receptors for traditional and nonclassical MHCs. Traditional MHCs are HLA-A, HLA-B, HLA-C; nonclassical MHCs are HLA-G (Zhang, Tong and Wu, 2009). A portion of these receptors are specific for explicit HLA subtypes. The vast majority of these receptors are predominant. Standard cells show MHC 1 class, subsequently are perceived by these receptors and characteristic executing is repressed. LIR or ILT or leukocyte inhibitory receptors Work as inhibitory receptors on human normal executioner cells. These receptors get communicated on mononuclear leukocyte cells of human. Cytotoxic action of recently disconnected T cell reproductions can be repressed by the counter LIR-1mAb (Lebbink et al., 2007). These receptors give guideline component of T effector cells and restrain undesirable reactions mediated by antigen explicit T cells. References Kramer, P., Winger, V. furthermore, Reuben, J. (2009). PI3K limits TNF-creation in CD16-enacted monocytes.European Journal of Immunology, 39(2), pp.561-570. Lebbink, R., de Ruiter, T., Kaptijn, G., Bihan, D., Jansen, C., Lenting, P. also, Meyaard, L. (2007). Mouse leukocyte-related Ig-like receptor-1 (mLAIR-1) capacities as an inhibitory collagen-restricting receptor on safe cells.International Immunology, 19(8), pp.1011-1019. Lieto, L. (2005). CD94 1A/1B: a window opens into NK-cell development.Blood, 106(10), pp.3338-3339. Zhang, X., Tong, C. also, Wu, T. (2009). 178-P: The impact of inhibitory and actuating KIRs on haploidentical hematopoietic undifferentiated organism transplantation.Human Immunology, 70, p.S101.

Communication and Information Technology Essay

Innovative progression have improved and facilitated the correspondence procedure. With the world spinning around innovation, practically the sum total of what errands have been streamlined thus diminishing the quantity of hours that one can play out a specific assignment. It has helped in the sorting out data, in this way empowering access and recovery of data simple. The utilization of innovation has helped numerous associations cut on costs simultaneously expanding productivity and expeditiousness in administration conveyance. In the clinical field, a large portion of the up to the standard emergency clinics or human services frameworks have embraced the utilization of innovation in conveying of their administrations. This has achieved serenely and the sentiment of thankfulness to the patient or the individual who is being filled in as it gives an atmosphere of significant worth for cash and the feeling of grasp of innovation in this mechanical period. Electronic Medical Records is one of these innovations (Kluge, 2001). With the ability to hold boundless data and having the option to be changed to fit the current need, this innovation has helped in the human services experts to convey benefits in an increasingly sorted out way and without having delays when contrasted with if everything was done physically. Importantly, this decreases costs and improves the image of the association simultaneously cultivating checking capacity of the association of the quantity of customers visiting the medicinal services office. Electronic Medical Record is automated sort of data keeping in which data is compacted as it is changed over in an advanced configuration. This takes into account utilization of insignificant space while keeping the workplace of activity perfect, clean and appealing (Fins, 2008). This production of room empowers the extension of administrations offered in the human services office as there is more space of activity. Access of data turns out to be simple and advantageous consequently expanding the assurance of the staff in administration conveyance. It balances the chance of submitting superfluous slip-ups while conveying administrations in light of written by hand records which are not intelligible. This program makes it conceivable exchange data starting with one medicinal services framework then onto the next hence making it conceivable to treat patients in the most limited time conceivable as their clinical records are conveyed in the briefest time conceivable electronically. By utilization of this innovation, it is feasible for guardians to screen their kids’ prosperity without having additional expense of venturing out to where they are to beware of their advancement. It likewise makes it workable for patients to survey their clinical record and furthermore get their outcomes absent a lot of issue of holding up till they are given to them physically. Other electronic correspondence conveyance administrations like the utilization of voice over have helped in the decrease of the measure of work that one does in calling patients physically with the goal that they can be taken care of. It is only a straightforward undertaking of simply declaring a patients name and they go to the comparing room in which they will be served. This has expanded proficiency and viability in serving customers (Fins, 2008). This sets a sort of a request which they patients follow and considering simple spread of data, noisy enough for everybody to hear, along these lines, patients don't need to endure the frustration of not having heard their names being referenced by a guest genuinely since this framework is fitted with speakers sufficiently uproarious to be heard obviously. Different advances like the Practice the executives programming guarantee the smooth running of the human services framework giving clinical specialists an unassuming time in their procedure every day. This wads off conceivable outcomes of disarray and lets them (clinical experts) work in a methodical way. The data which this product can deal with is comprehensive and doesn't just incorporate the client’s bio information yet in addition different parts of the medicinal services association like bills and exchanges going on. (Klug, 2001) It works only a similar path as the EMR just that it includes the administration part of social insurance framework in its day by day tasks. Aside from keeping a track on patients’ conditions and arrangements, the framework is utilized to create bills and keep a record on the equivalent so that thee reports can be utilized at whatever point need emerges. It keeps each exchange and movement on record with the goal that it gets workable for any expert to realize what was done the earlier day and by who, which patient was taken care of and by who so he/she can know precisely where to begin as concerns a particular errand. This similarly as the EMRs has a method of reducing expenses and expanding viability. This is on the grounds that all data as concerns any patient is put away electronically and recovered easily when need emerges, subsequently maintaining a strategic distance from the chance of befuddling one’s clinical information with another people (Fins, 2008). This empowers a clinical specialist to endorse the correct medication to the ideal individual while simultaneously taking into account age of data about the correct bills for the customer in understanding to the clinical methodology and drug agreed to that person. Different frameworks like the electronic wellbeing frameworks keep a full clinical history of a patient. It keeps fundamental data that can be utilized by the specialist or any clinical expert to offer fast and compelling analysis of a patient. All human services reports about a specific patient are put away in this framework including drugs recommended to the patient each time he/she goes to that medicinal services office. It is additionally comprehensive of all test consequences of that specific patient just as x-beams and the reaction of the patient towards a specific drug. This data is fundamental for up to level social insurance treatment of any patient. It keeps off the anguish of a patient for responding to dull inquiries regarding their past clinical history each time they visit a medicinal services office, as data about them is put away electronically and recovered on each visit. This clinical history is refreshed chance to time on the events that a customer visits to look for treatment. The utilization of electronic innovation in human services frameworks has a greater number of experts than cons. This is on the grounds that as identified above, it has focal points to both the customer and the social insurance office. The way that it expands proficiency and adequacy can not be underscored while simultaneously decreasing working expenses of the office. Customers are served exactly as they would prefer and keeping in mind that their clinical record is kept securely and is recovered during the period of scarcity no sweat (Kluge, 2001). One of the significant burdens is that data about a patient can be duplicated malignantly and messed with. On the off chance that the whole framework should separate, at that point volumes and volumes of data are lost. It would be something to be thankful for if all the above framework could be coordinated into one piece. This will ease activity significantly more as all the tasks are under a single tick of a ‘mouse’. It could likewise be improved so that customers can get to their data any place and at whatever point they are. Reference Fins, J. (2008). Web of Care: How Will the Electronic Medical Record Change Medicine? The Hastings Center Report, Vol. 38, pp. 67-88 Kluge, E. (2001). The Ethics of Electronic Patient Record

Unmanned Drones: Immoral?

Jordan Morris Dr. Flores Eng 103 February 27, 2013 Unmanned Drones: Immoral? I decided to inquire about two articles that take rival sides on the utilization of strategic unmanned ethereal vehicle rambles that are being utilized in battle over oceans seeing as how there is so much contention encompassing this theme in the news these days. â€Å"The unmanned aeronautical vehicle otherwise called UAV is an airplane with no pilot ready. UAV’s can be remote controlled or fly independently dependent on pre-modified flight plans† (www. theuav. com). These unmanned â€Å"drones† are utilized in the military for various things including insight assembling and assaults psychological oppressor groups.The first article is the better of the two with regards to persuading the peruser. Despite the fact that military aircraft have the upside of and experienced pilot in the driver's seat, unmanned automatons are increasingly exact, more affordable and more secure than military a ircraft. The purpose of the principal article â€Å"Five Myths about Obama’s Drone War† (Washington Post) is to persuade the peruser that it is alright to utilize rambles in battle. He discusses how during wartimes it is significant for the weaponry to advance, from slingshots to bow and bolts to firearms to military aircraft to unmanned drones.He says, â€Å"that from a good and moral point of view rambles are practically zero not the same as rifles, planes or tanks. † (Washington Post) He likewise says that automatons are the absolute most exact weaponry utilized in battle postulations day however doesn’t truly give measurements. â€Å"Drones ought not give us a misguided feeling that all is well and good. The knowledge required for focusing on may require U. S. boots on the ground. † (Washington Post) Drones are substantially less costly than warrior airplanes so it would bode well for a less fortunate nation to put resources into building rambl es rather than contenders. This presents an issue for the U. S. ecause we are progressively inclined to assaults, as observed on September 11, 2001. In the primary article Mark R. Jacobson records 5 legends that have been started about the utilization of these automatons, and afterward clarifies his view on every one. Jacobson address’s the announcement â€Å"Drones are immoral,† which is an incredible method to begin the article seeing as how that’s what a great many people see them to be. He says, â€Å"Drones are neither self-ruling executioner robots nor aware creatures settling on last chance choices. However, with the â€Å"Terminator†-like undertones of the term, it is anything but difficult to overlook that these vehicles are flown by means of remote control by somewhere in the range of 1,300 Air Force pilots.Drones are a development in military innovation, not an upheaval in fighting. † This announcement is a prime case of Logos, the intri gue to rationale, since he adopts an exceptionally direct strategy to the current point. He at that point proceeds to utilize Ethos while tending to the announcement, â€Å"Drones permit us to battle wars without risk. † Jacobson states that, â€Å"Drones ought not give a misguided feeling that all is well and good. The insight required for focusing on may require U. S. boot on the ground. † This describes the possibility of a network despite everything being expected to pick up data and do some â€Å"dirty work† for there to try and be the requirement for an automaton strike.In the second article â€Å"Drone Strikes: What’s the Law? † (LA Times) creator Vicki Divoll examines the execution of U. S. resident Anwar Awlaki by our administration in an automaton assault. Her article manages the fifth Amendment’s advice: No American resident will â€Å"be denied of life, freedom or the property without fair treatment of law. † Her style of composing is increasingly similar to the Tolmin Model of Argument. This article had significantly more feeling included which made the peruser much progressively occupied with what the writer was talking about.Instead of writing in a manner that may concentrate absolutely on the various sorts of bids, the subsequent article is written in a way that centers more around an underlying case that is sponsored by help proof. Furthermore, the writer specifies Awlaki’s story, which gives an enthusiastic contribution to the peruser to stay locked in. The author’s guarantee in the subsequent article is that American residents ought to be qualified for their protected rights. Her tale about how Anwar Awlaki, an American resident, was purportedly focused on and executed exhibits the way that few out of every odd resident is being dealt with equally.She proceeds to offer help for her case by examining, â€Å"the Supreme Court case Hamdi versus Rumsfeld, a 2004 Bush-time Supreme Co urt choice, to legitimize that the administration accepts that there are no fair treatment issues with the automaton program. Be that as it may, the reminder journalists commit a reprehensible error: They filter out the choice, dismissing the core of what the judges said. † For the situation she makes reference to, Yasir Hamdi, a U. S. resident captured on the front line in Afghanistan, set out to challenge his inconclusive confinement in an American military office as a foe combatant.The organization at the time contended that, in wartime, the official alone ought to figure out who the foe is and what measure can to be utilized against him. The court differ and sent Hamdi’s case to a lower court for an audit of true exactness of his adversary soldier assignment. This audit never occurred and Hamdi was ousted. The Supreme Court's thinking in Hamdi remains the most material legitimate model that applies to focused killings. Divoll composes, â€Å"Significantly, eight of the nine judges concurred that Hamdi was qualified for an unprejudiced survey, outside the official branch, of the realities of the case.Only Justice Clarence Thomas purchased the Bush organization's hypothesis of official force. Equity Sandra Day O'Connor, composing the foremost supposition, helped us to remember the court's decades-long reprimand: â€Å"A condition of war is certainly not an unlimited free pass for the president with regards to the privileges of the country's residents. † O'Connor further clarified how the fair treatment statement works in wartime when the official branch is making an assurance about the destiny of an American resident. Hamdi's enthusiasm for freedom, she composed, must be adjusted against the requirements of the official in battling a war.You needn't bother with a law degree to apply that thinking to focused killings. On the off chance that the official can't act alone when an American's freedom is in question in the post-9/11 War on Terr orism, the Supreme Court would be at any rate as concerned when an American's life is on the line. The court has consistently decided that the more essential the individual enthusiasm in question, the more ‘process’ is expected. † All this is an incredible wellspring of help for Divoll’s guarantee. The subsequent article had considerably more verifiable proof to back up the author’s introductory case yet still gave a feeling of feeling to keep the peruser interested.The two stories gave by Divoll were ideal models in which the writer could allude to and call attention to the defects in our framework. In spite of the fact that she doesn’t come directly out and conspicuously state it, I accept that the creator would concur in my past proclamation that it is alright to utilize unmanned strategic automatons on American residents just in the event that they have wouldn't practice their entitlement to fair treatment. Work Cited Page 1. http://www. t heuav. com/2. http://articles. washingtonpost. com/2013-02-08/sentiments/36988550_1_drone-strikes-ramble pilots-regular citizen setbacks (Washington Post) 3.

Theology of the Body Free Essays

Opportunity, truth, blessing, fellowship, respect, love, individual, which means: these are altogether topics which are consistently found all through the compositions of Pope John Paul II. They were there even before he became Pope. As Cardinal Karol Wojtyla he was compelling in the composition of a few archives from Vatican II, not the least of which was Gaudium et Spes †the Pastoral Constitution on the Church in the Modern World †from which he never feels worn out on citing in his numerous encyclicals and missional letters. We will compose a custom article test on Religious philosophy of the Body or on the other hand any comparative subject just for you Request Now â€Å"Man is the main animal on earth which God willed for tself, [and he] can't completely end up with the exception of through a true endowment of himself. † (Gaudium et Spes 24) We should initially know the reason for our reality and what we were made for in the event that we are to carry on with a completely significant life. Pope John Paul II investigates the motivation behind our reality in his Theology of the Body, which comprises of 129 general Wednesday crowds conveyed by him during the initial five years of his pontificate. Before his political race as pope, John Paul II composed a book, L o v e and Responsibility.In Love and Responsibility K a rol Wo j t y l a p despises the Catholic Church’s instructing on affection and sexuality such that bodes well to present day man. Wojtyla stresses the pride of the individual and shows that it is so essential to live our sexuality in a manner which maintains and asserts the other individual. In reality, the genuine sweetheart will never utilize someone else or treat her as an unfortunate obligation. In his Theology of the Body John Paul II delves profound into the importance of being a human individual dependent on Scripture. As an individual with a body and soul, made in the picture and ikeness of God, we locate the significance of life through discov ering imaging God and what our bodies have to do with it. We not just picture God through the endowment of choice, yet in addition through being in fellowship with others. â€Å"To be human intends to be called to relational communio . † Why? Since God himself is a fellowship of people in the Trinity. He clarifies, â€Å"Man turned into the â€Å"image and likeness† of God through his own mankind, yet additionally through the fellowship of people which man and lady structure directly from the earliest starting point. † (TOB, Nov. 4, 1979) â€Å"Man Cannot Live Without Love† A â€Å"communion of persons† happens when two individuals unreservedly offer themselves to one another and acknowledge each other in adoration. Truth be told, genuine romance comprises decisively in this shared selfgift. As we find in the Gospels, the central matter of the Christian life is to adore. John Paul II’s other most loved statement from Gaudium et Spes discloses to us that, â€Å"Christ†¦fully uncovers man to man himself and makes his incomparable calling understood. †What does Christ uncover yet that, â€Å"Greater love has no man than this, that a man set out his life for his companions. †? (Jn. 5:13) It is Christ himself who uncovers to us our fundamental work as people by offering himself to us in his demise on the Cross. Through his Theology of the Body, John Paul II tries to present to us the Gospel message of affection in another, profound, and significant way. He realizes that affection is the thing that all individuals look for. He ventures to such an extreme as to state, â€Å"Man can't live without adoration. He stays a being that is unfathomable for himself, his life is silly, if love isn't uncovered to him, in the event that he doesn't experience love, in the event that he doesn't encounter love How significant it is to live our sexuality in way which maintains and asserts the other individual! To be sure, the genuine darling will never utilize someone else or treat her as an unfortunate obligation. Pope John Paul II’s Theology of the BodyThis distribution  © 2003 Resurrection Publications P. O. Box 21357 †¢ Cheyenne, WY 82003-7026 For more data, if it's not too much trouble get in touch with us at: without toll: 1-866-333-6392 †¢ www. theologyofthebody. net Study bunches meet normally to talk about the Theology of the Body. Visit www. theologyofthebody. net for data on a gathering close to you †or how to begin one of your own. Step by step instructions to refer to Theology of the Body, Papers

Heart of Darkness – Lies

As indicated by Merriam-Webster’s Dictionary, a falsehood is a false or incorrect articulation that might possibly be accepted valid by the speaker or it is something that deludes or beguiles. At the end of the day, a falsehood is a misrepresentation. In life lies are told for a wide range of reasons. In fiction they give somewhat more body to the plot. In Conrad's Heart of Darkness, Marlow disdains lies and in this way just lets them know in uncommon conditions. The falsehood show that Marlow, despite the fact that he has been moved by insidious, he is as yet a decent man himself; that he never really lies, however he lets others keep on accepting what they as of now accept; and by doing this, it causes him legitimize the untruths. Marlow, in his story, interferes with himself and says â€Å"You realize I detest, hate, and can't hold up under a falsehood. † If understanding this and just this announcement alone, we can unmistakably observe Marlow doesn't care for lies. Marlow feels there is a â€Å"taint of death, and a kind of mortality in lies. Lying causes him to feel â€Å"miserable and wiped out, such as gnawing something spoiled would do. † Since he feels along these lines, we as the peruser realize that he would just lie in uncommon conditions. The falsehood was advised to Kurtz’s â€Å"intended† with the goal that the adored picture of her dead life partner would not be decimated. She has hung tight in any event two years for her darling to come back from Africa, and now he is dead. During this time she has developed his picture in her brain. To her, Kurtz is a man to be appreciated. She feels it would be â€Å"impossible not to cherish him. She was glad to have been locked in to Kurtz, and would be stunned to learn of the awful things he had done in the wilderness. Marlow needed to choose if he should come clean with her about Kurtz and cause her significantly more prominent trouble, or let her continue accepting that he was to be sure a decent man. This is an unprecedented condition, thus one in which Marlow could lie. The noteworthiness of this falsehood is that it would fill no need to come clean, so Marlow doesn't. Reality wouldn’t matter in light of the fact that Kurtz is dead and to come clean would just damage an honest lady who had no clue that her life partner had a malevolent heart. She imagined that he was adored and respected by everybody who knew him, so on the off chance that she would have scholarly of the awful things he had done, it would unceasingly decimate her. Marlow additionally indicated his great side by not coming clean with her about Kurtz. This was a decent closure of the novel since it implies that despite the fact that Marlow has met a man with a â€Å"Heart of Darkness,† and that much in the wake of confronting his own haziness, he has come out of the wilderness ethically unaltered, generally. He is as yet a decent person with sentiments and a feeling of good and bad. On the off chance that we read intently, we see that Marlow never really lied. He basically permitted others to keep on accepting a misrepresentation. The â€Å"intended† thought Kurtz as a decent man, and Marlow permitted her to keep on accepting only that. Likewise the â€Å"intended† stays as accidental of reality as she generally has, and stays a piece of the premonition haziness with which the story closes. As a noble man, Marlow feels that ladies are to be shielded and protected from any disagreeableness, he expresses that â€Å"the ladies are withdrawn from truth†, that they are unequipped for managing any reality. Since he never really lied, he was better ready to legitimize them to himself. Taking everything into account, Marlow detests lies, and just lets them know in remarkable conditions. At the point when he lies, it is for other people, not for himself. This shows he is a common and kind person. Tragically all untruths are not told with such noble reason. The world would be a superior spot on the off chance that they were. However, Marlow’s mission for truth is never truly satisfied toward the finish of the novel in view of the untruth. Reality didn't liberate him; rather it put him further into the â€Å"darkness†.

And The Students Stop Blogging Richmond Writing

And The Students Stop Blogging Richmond Writing At the very time that I feel most comfortable teaching with blogs, I read that blogging is on the decline among the very demographic I teach. I like Twitter and other sites for short notices, but few ideas can be expressed in 140 characters. Perhaps the unexamined life is not worth living by Socrates would fit in a Tweet. The Apology would not. As usual, Ill blame what I call a life of constant interruption. My Neo-Luddite side, and it is a prominent side, finds some cold comfort in the warnings of writers and thinkers such as Nicholas Carr, Mark Edmundson, and Sven Birkerts. Even tech-savvy Sherry Turkles book, Alone Together, warns of the shallowness of our social networking habits. I look out for such writing, so I quickly ran across Gregory Palmerinos article, Teaching Bartleby to Write, in the January 2011 issue of College English. Palmerino writes of his students who would prefer not to remember to hand in writing because of their complex and distractable lives.   Such students rarely linger in my classes after the add/drop period; the writing is plain on the syllabus about the consequences of Bartlebys passive-aggressive preference of preferring not to do. While I do find a kindred spirit in Palmerino, I part ways with his resistance to new technologies in the writing classroom. Blogging provides one excellent example of a type of writing that demands focus. Distraction here, in a post, can be as fatal as it would be in a short story or analytical essay.   So far, however, none of my students Tweet or use Facebook status-updates for any sort of serious discourse.   I doubt they ever will. In print and online, we who cherish nuance and complexity in language need do something. Rejecting the new is not the answer.   So for now, my students, at least, will keep posting to blogs and replying to each other.

And The Students Stop Blogging Richmond Writing

And The Students Stop Blogging Richmond Writing At the very time that I feel most comfortable teaching with blogs, I read that blogging is on the decline among the very demographic I teach. I like Twitter and other sites for short notices, but few ideas can be expressed in 140 characters. Perhaps the unexamined life is not worth living by Socrates would fit in a Tweet. The Apology would not. As usual, Ill blame what I call a life of constant interruption. My Neo-Luddite side, and it is a prominent side, finds some cold comfort in the warnings of writers and thinkers such as Nicholas Carr, Mark Edmundson, and Sven Birkerts. Even tech-savvy Sherry Turkles book, Alone Together, warns of the shallowness of our social networking habits. I look out for such writing, so I quickly ran across Gregory Palmerinos article, Teaching Bartleby to Write, in the January 2011 issue of College English. Palmerino writes of his students who would prefer not to remember to hand in writing because of their complex and distractable lives.   Such students rarely linger in my classes after the add/drop period; the writing is plain on the syllabus about the consequences of Bartlebys passive-aggressive preference of preferring not to do. While I do find a kindred spirit in Palmerino, I part ways with his resistance to new technologies in the writing classroom. Blogging provides one excellent example of a type of writing that demands focus. Distraction here, in a post, can be as fatal as it would be in a short story or analytical essay.   So far, however, none of my students Tweet or use Facebook status-updates for any sort of serious discourse.   I doubt they ever will. In print and online, we who cherish nuance and complexity in language need do something. Rejecting the new is not the answer.   So for now, my students, at least, will keep posting to blogs and replying to each other.